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Psychedelics in 2025: Psychedelic medicine in the US has reached a crucial inflection point as of May 2025, with ketamine firmly established in mainstream treatment, psilocybin progressing toward potential FDA approval, and MDMA facing regulatory setbacks. Ketamine received expanded FDA approval as monotherapy for treatment-resistant depression in January 2025, while psilocybin therapy is accessible through licensed service centers in Oregon and Colorado with COMPASS Pathways' Phase 3 trial results expected by mid-2025. MDMA faces additional years of development after the FDA rejected Lykos Therapeutics' application in August 2024.

Overcome AI anxiety today. AI anxiety is a growing psychological phenomenon affecting millions of professionals worldwide as artificial intelligence rapidly transforms the workplace. You wake up in the morning, check the news, and see another headline about AI automating jobs. Your stomach tightens as you wonder: 'Am I next?'

The Psychedelic Comeback Reaches Mainstream Medicine. The psychedelic comeback is transforming mental healthcare in 2025, with MDMA, psilocybin, and ketamine therapy now available in 32 states. After decades of prohibition, these powerful substances have reemerged as legitimate treatment options for depression, PTSD, and anxiety disorders—backed by impressive clinical results and unprecedented regulatory support.

Major insurers now cover psychedelic-assisted therapy for treatment-resistant depression and PTSD, making these breakthrough treatments accessible to millions of Americans who previously had limited options. This psychedelic comeback represents the most significant paradigm shift in mental health treatment since the introduction of SSRIs in the 1980s.

Finding the right balance of peak experience, effective practice, and flow states is essential for sustained gains in the long run. Why? People are needy. We want it all; we want it now; we want it to last forever; and we want it for free. This is the calculus of biology, but never confuse short-term appetites with lifelong strategy.

Real gains have a half-life. They’re perishable. Preserving them requires effort, intelligence, and a strategy. To make our efforts productive over the long haul, we need the right combination of peak experiences, effective regular practice habits, and the ability to create flow states to accelerate the process.

The trip comes and goes, but preparation and integration make all the difference.

A life best lived is one that is examined, and improved as it is lived. An examined life includes regular small doses of introspection punctuated with experiences that can shake our world view and view of ourselves to the core. Used judiciously, psychedelics can offer such planned experiences.

At first, you weren’t here — now, here you are — but soon, you’ll be gone forever. Sunrise, sunset. We all die.

But in the space of your life, there is also a space called your mind, where everything interesting happens. Your mind is where your uniquely personal and private experience roils, like an eddy in a larger river of conscious people and beings popping in and out of life. It’s this conscious experience that serious students of meditation seek to understand.

Whether composing a tweet, an email, a blog post, a business case, an essay, or a book, you must connect powerfully and viscerally to what a reader stands to gain or lose by your proposition—real or imagined. Persuasive writing speaks to your reader’s visceral emotions, and more than just getting them to agree with you, it gets them moving in the same direction. Effectively, your idea becomes your reader’s idea and compels him or her to: start, stop, buy, act, change, invest, or avoid something you are saying. But how? Here are four things to think about when writing to persuade your audience.

How would you describe your relationship to death in general, and your death specifically? Is it healthy? How did thoughts of your extinction influence how you lived last week, or how you might live next week? Does the shortening of your remaining time on earth make your life richer? Are you at ease with the specter of the world continuing without you, or do you crowd it out of your mind?

According to Google Autofill, millions of people have asked the astonishingly painful and intimate question. Type: “how can I learn”... and you will see “to love myself” among other high-ranking inquiries around such topics as coding, and languages. This is tragic—and if you are reading this now, it is likely a thought you’ve had at one time or another. You can learn to love yourself.